Posted by Chantel M. research contributed US National Library of Medicine
National Institutes of Health
In a population-based case-control study to evaluate phytoestrogen intake from foods
and supplements and epithelial ovarian cancer risk of a total of 205
cases and 390 controls were included in analyses., posted in PubMed, there was a suggestion of an inverse association with total phytoestrogen consumption (from foods
and supplements), with an odds ratio (OR) of 0.62 (95% CI: 0.38-1.00; p
for trend: 0.04) for the highest vs. lowest tertile of consumption,
after adjusting for reproductive covariates, age, race, education, BMI,
and total energy. Further adjustment for smoking and physical activity
attenuated risk estimates (OR: 0.66; 95% CI: 0.41-1.08). There was
little evidence of an inverse association for isoflavones, lignans, or
coumestrol.
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