Overcome Male Infertility - The Human Zona Pellucida Binding Test

Posted by Chantel Martiromo

Fertility is a natural process to insure the survival of human species. Through natural selection, we produce many offspring when the reproductive system works at it's peak in the suitable environment with plenty of food around. On the other hand, the reproductive system may completely shut down or work at it's minimum state and we produce less offspring, when the environment is hostile including less foods around, war, epidemic, but regardless of all these factors, most women are capable of conceiving during their menstrual cycle before menopause.

The aim of the test is to exam how the sperm bind to outer layer of the egg, including hemizona assay.

I. Procedure
The test is necessary if the men is found to be infertile with either reduced sperm count, motility and morphology alone, or in combination and is classified with unexplained causes. The sperm and egg are collected from a couple and is used to see the sperm penetration in IVF.

II. Diagnosis
The process of human fertilization, sperm must bind to the zona pellucida, undergo the acrosome reaction, penetrate the the out layer of the egg and then fuse with the oolemma. The process is observed and recorded. If the sperm can not penetrate the egg then other testes may be needed or conception may be required more technical support. If the sperm has no problem in egg penetrating, then IUI or IVF is the best choice in assisting the fertilization for a unfertilized couple.

III. Risk
Although the successful rate to conceive is very high, if a couple pass the humanzona pellucida binding test, but it is not 100% guaranteed, since for a couple to get conceive, it takes more than human zona pellucida test.

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