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Wednesday, March 16, 2016

Women Health: The Smoothie of Green Tea, Sweet Potato and Flax Seed for Reduced Risk and Treatment of Atrophic Vaginitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Reduced Risk of consequences of Atrophic Vaginitis  
Yield: 2 servings (about 8 ounces each)
1 1/4  cup sweet potato
1/4 cup flax seed
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Atrophic Vaginitis is an inflammation of the vagina and the outer urinary tract due to decreased production of estrogen induced thinning and shrinking of the tissues, and decreased lubricationas a result of aging in women..

The finding of a natural source for reduced risk and treatment of Atrophic Vaginitis to replace the oral hormone replacement therapy (HRT), has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Strong evidences of number of renowned institutions suggested that natural sources, including a gel, containing hyaluronic acid(1)(8), liposomes,phytoestrogens from Humulus lupulus extract, and Vitamin E, may be effective for treatment of Atrophic Vaginitis applied topically (1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, vigina dryness, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).

Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve depression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor  are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. According to the joint study led by the Seton Hall University, theaflavin digallate isolated from green expressed anti viral activity against inflammation in stable at vaginal pH, and inhibited HSV-1 viral particles(9).
Its epigallocatechin gallate (EGCg) also enhanced the antifungal effect of amphotericin B or fluconazole against antimycotic-susceptible and -resistant C. albicans(10).

The effectiveness of Green Tea, Sweet Potato and Flax Seed may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  Atrophic Vaginitis  with little or no adverse effects.

Intake of Smoothie of  Green Tea, Sweet Potato and Flax Seed may Reduced Risk and treatment of Atrophic Vaginitis due to aging
Life style and dietary patter change are recommended.

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References
(1) Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy by Morali G1, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, Marrè GB.(PubMed)
(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)
(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)
(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)
(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)
(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)
(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)
(8) The effect of vaginally administered genistein in comparison with hyaluronic acid on atrophic epithelium in postmenopause by Le Donne M1, Caruso C, Mancuso A, Costa G, Iemmo R, Pizzimenti G, Cavallari V.(PubMed)
(9) Antiviral activity of theaflavin digallate against herpes simplex virus type 1 by de Oliveira A1, Prince D1, Lo CY2, Lee LH3, Chu TC4.(PubMed)
(10) Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans by Hirasawa M1, Takada K.(PubMed)

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