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Monday, May 16, 2016

The Smoothie of Alfalfa Sprouts Juice, Flax seed and Organic Soy Milk for Prevention and Treatment of Glomerulocystic kidney disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Glomerulocystic kidney disease
Yield: 2 servings (about 8 ounces each)
4/5 cup Alfalfa Sprouts Juice
1/4  cup fax seed
1 cup organic soy milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Glomerulocystic kidney disease has been running into many obstacles, many ingredients showed initially with promising result in studies have not produced same potentials in large sample size and mutli centers human trials.
Glomerulocystic kidney disease is a rare cystic disease of kidney as a result of genetic mutation of gene (PKD1 and PKD2) or accquired due to intake of certain  medication by the mother such as phenacetin(1).

Phytoestrogens have shown to attenuate cyst pathogenesis and progression of Glomerulocystic kidney disease in animal studies, according to the West Virginia University(8).

Soy protein made from soybean dehulled and defatted meal may be effective for prevention and treatment of Glomerulocystic kidney disease(2). According to the University of Guelph, soy protein is effective in reduced the renal enlargement and cyst development associated with progression of polycystic kidney disease(3).
Dr. Pengted  CY and colleagues at the University of Manitoba suggested, regular intake of soy meal ameliorated the progression of polycystic kidney disease through selectively inhibited renal prostanoids and cyclooxygenases expression(4) in  relief pain and inflammation.

Omega-3 polyunsaturated fatty acids found abundantly in flax, may also attenuated the progression and against bone loss associated with early Glomerulocystic kidney disease(5) through up-regulate renal (cyclooxygenases-2) COX-2 gene and protein levels(7). According to the Royal Brisbane and Women's Hospital, Brisbane, in vitro and in vivo experimental studies support the efficacy of omega-3 polyunsaturated fatty acids on inflammatory pathways involved with the progression of kidney disease, including Glomerulocystic kidney disease(6) but well-designed, adequately powered, randomized, controlled clinical trials are necessary for further investigation.

The effectiveness of Alfalfa Sprouts, Fax Seed and Organic Soy Milk may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk  and treatment of Glomerulocystic kidney disease with little or no adverse effects.
People who are at increased risk of Glomerulocystic kidney disease  due to sexual active with many partners,..... should drink the smoothie twice a day and people with Glomerulocystic kidney disease should drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

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References
(1) Glomerulocystic kidney disease by John J. Bissler,1 Brian J. Siroky,1 and Hong Yin2(PubMed)
(2) Dietary soy protein effects on inherited polycystic kidney disease are influenced by gender andprotein level by Aukema HM1, Housini I, Rawling JM(PubMed)
(3) Effect of dietary soy protein and genistein on disease progression in mice with polycystic kidney disease by Tomobe K1, Philbrick DJ, Ogborn MR, Takahashi H, Holub BJ.(PubMed)
(4) Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease by Peng CY1, Sankaran D, Ogborn MR, Aukema HM.(PubMed)
(5) Feeding soy protein isolate and oils rich in omega-3 polyunsaturated fatty acids affected mineral balance, but not bone in a rat model of autosomal recessive polycystic kidney disease by Maditz KH1, Smith BJ2, Miller M3, Oldaker C4, Tou JC5.(PubMed)
(6) Omega-3 polyunsaturated fatty acids in the treatment of kidney disease. by Fassett RG1, Gobe GC, Peake JM, Coombes JS.(PubMed)
(7) COX-2 expression in cystic kidneys is dependent on dietary n-3 fatty acid composition by Sankaran D1, Lu J, Ogborn MR, Aukema HM.(PubMed)
(8) Evidence for a role of proteins, lipids, and phytochemicals in the prevention of polycystic kidney disease progression and severity by Maditz KH1, Gigliotti JC, Tou JC.(PubMed)

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