Get Pregnant Naturally

Get Pregnant Naturally
".....Utilizing Traditional Chinese Medicine in Tonifying Energy flow to the Reproductive System Channels In Men and Women for Natural Conception, including Couple Who were diagnosed with Unexplained causes of Infertility...." Chantel M.

Permanent Unwanted Tattoo Removal by Tattoo Expert

Permanent Unwanted Tattoo Removal by Tattoo Expert
Safely, Painlessly, Laserlessly and Naturally in Removing any Unwanted Tattoos in 2 to 8 Weeks, Guaranteed

Thursday, March 31, 2016

The Smoothie of Green Tea, Grape and Peppermint Herbal Tea for Prevention and Treatment of Hypoalbuminemia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Hypoalbuminemia
Yield: 2 servings (about 8 ounces each)

1 1/2 cups grape
1/2 cup peppermint herbal tea
1/2 cup green tea drink (Make from 2 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Hypoalbuminemia has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Green Tea, Grape and Peppermint Herbal Tea may be the next generation of natural ingredients for prevention and treatment of Hypoalbuminemia.

Hypoalbuminemia is a health condition with extreme low buminemia, a major protein in the human body which plays an important role in regulated colloidal osmotic pressure of blood. According to the Los Angeles Biomedical Institute at Harbor-UCLA Medical Center, a short-term in-center nutritional intervention significantly improve levels of albuminemia in hypoalbuminemic MHD patients(1).
Persistent hypoalbuminemia may worsen the activity and increase oxidative cell damage. in chronic hemodialysis patients(2).
In fact, patients with hypoalbuminaemia are associated to increased expression of pro inflammatory cytokines and significantly correlate with low level of serum albumin, according to the cross-sectional study was performed on 76 Japanese PD patients(3).
Green tea, the powerful and natural agent not only has exhibited more efficacious than dexamethasone an established anti-inflammatory drug(4) but also increased levels of albuminemia through its anti inflammatory effects, according to Dr. Victor R. Preedy(5).

Resveratrol, a polyphenolic compound and antioxidant present in grapes and blueberry. According to Dr. Nihei T and professors at the Tokyo Noko University, resveratrol may be a potent anti-glomerulonephritic food factor capable of suppressing hypoalbuminemia through it effects in reduced urinary protein excretion and increased serum albumin concentration(6).
Furthermore, Liverubin (standardized silymarin (peppermint)) expressed significant anti mild, temporary hepatic failure (MTHF) induced decreased levels of albumin and other aspects after 4 weeks of application(7).

The effectiveness of Green Tea, Grape and Peppermint Herbal Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of albuminuria with little or no adverse effects.

People who are at high risk of Hypoalbuminemia due to aging, weaken reno function... should drink at least one serving daily and People with Hypoalbuminemiashould drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.



References
(1) An anti-inflammatory and antioxidant nutritional supplement for hypoalbuminemic hemodialysis patients: a pilot/feasibility study by Kalantar-Zadeh K1, Braglia A, Chow J, Kwon O, Kuwae N, Colman S, Cockram DB, Kopple JD.(PubMed)
(2) Hypoalbuminemia accelerates erythrocyte membrane lipid peroxidation in chronic hemodialysis patients by Soejima A1, Matsuzawa N, Miyake N, Karube M, Fukuoka K, Nakabayashi K, Kitamoto K, Nagasawa T.(PubMed)
(3) Inflammatory factors for hypoalbuminemia in Japanese peritoneal dialysis patients by Shioya M1, Yoshida T, Kasai K, Furuya R, Kato A, Mori N, Matsumoto Y, Kumagai H.(PubMed)
(4) Different types of tea products attenuate inflammation induced in Trypanosoma brucei infected mice by Karori SM1, Ngure RM, Wachira FN, Wanyoko JK, Mwangi JN.(PubMed)
(5) Tea in Health and Disease Preventionedited by Victor R. Preedy
(6) Inhibitory effect of resveratrol on proteinuria, hypoalbuminemia and hyperlipidemia in nephritic rats by Nihei T1, Miura Y, Yagasaki K.(PubMed)

Wednesday, March 30, 2016

The Marvelous smoothie of Green tea, Blueberry and Apple for Reduced Risk and Treatment of Squamous cell skin cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for Squamous cell skin  cancer with little or no adverse effect.

Yield: 2 serving (about 8 ounce each)
1 cup blueberry
1/2 cup apple with peel on
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Squamous cell cancer has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Skin cancer is a medical condition of uncontrolled growth of abnormal skin cells and often detected at an early stage. Squamous cell cancer arises from the uncontrolled multiplication of transformed malignant cells in the middle layer of the epidermis.
Scientists working for some renowned institution may have found the ingredients from natural sources, including Green tea(1), blueberry(4) and apple(8) for reduced risk and treatment of Squamous cell cancer reported by most recent studies.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Gifu University, Graduate School of Medicine, epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, suppressed the RECK gene in signalling cancer invasion in oral squamous cell carcinoma cell lines, through multiple mechanism(1).
Dr. Vyas S and colleagues at the Panjab University also suggested that in the study of the protective effect of tea consumption on risk of cutaneous squamous cell carcinoma (SCC), (-)-Epicatechin-3-gallate, of the principal catechins of green tea exhibits cancer-preventive activities in various animal models(2), including Squamous cell cancer. In a topical experiment, use of green tea concentrate plus Capsicum (Capsol-T®) for approximately 14 days, exhibited the apoptotic of carcinoma responded(3).
Dr. Clifford JL and Dr. DiGiovanni J. said,"..., green tea polyphenols in mouse models of UV-induced and chemically induced skin carcinogenesis and results of perillyl alcohol in a phase IIa clinical trial-all pointing to the great promise of this exciting approach for better understanding of and preventing skin cancer"(4), in the study of the promise of natural products for blocking early events in skin carcinogenesis.

Blueberry is a flower plant, belong to the family Eriaceae and native to Northern America.
Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry has shown to exhibit anti human skin squamous cell carcinoma A431 xenograft effect through induced apoptosis of tumor cell(5).
Also in the human skin squamous cell carcinoma A431 xenografts, the phytochemical induced death of cancer cell line through upregulated the protein and mRNA expression of anti tumor expression proteins, p53 and to downregulated the protein and mRNA expression of the inhibitor of survivin gene(6).
Furthermore, resveratrol (RES), induced the processes critical for the growth inhibition of keratinocytes in vitro and in vivo of that showed a promising potential for reduced risk and progression of squamous cell skin cancer(7). 

Ursolic acid is a phytochemincal in the subclass of Triterpenoid, belongings to the group of Terpenes found abundantly in apples, basil, bilberries, cranberries, peppermint, lavender, oregano, hawthorn, prunes., etc. The antioxidant exhibited strong and effective antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor, according to Ichimaru Pharcos Company Ltd.(8).
Dr. Kowalczyk MC and the colleagues at the University of Texas Health Science Center at San Antonio in the study of skin cancer prevention suggested that the antioxidant protects the alternation of keratinocytes causes of tumor growth progression by acting as tumor inhibition in protected cells from hydrogen peroxide-induced DNA damage(9).

Taking altogether people who are at increased of squamous cell skin cancer  due to family history or gene mutation, occupation .....should drink at least one serving daily and people with squamous cell skin cancer should drink the smoothie as much as they can, depending to digestive toleration.
Change life style and diet pattern are also recommended.

References
(1) Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells by Kato K1, Long NK, Makita H, Toida M, Yamashita T, Hatakeyama D, Hara A, Mori H, Shibata T.(PubMed)
(2) Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice by Vyas S1, Manon B, Vir Singh T, Dev Sharma P, Sharma M.(PubMed)
(3) Response of carcinoma in situ (actinic keratosis) to green tea concentrate plus capsicum by Morré DJ1, Geilen CC, Welch AM, Morré DM.(PubMed)
(4) The promise of natural products for blocking early events in skin carcinogenesis by Clifford JL1, DiGiovanni J.(PubMed)
(5) [Study of apoptosis related factors regulatory mechanism of resveratrol to human skin squamous cell carcinomaA431 xenograft in nude mice].[Article in Chinese] by Hao YQ1, Huang WX, Feng HX, Zhang GH, Ning XH, Li HG, Hao CG, Li ZH.(PubMed)
(6) The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice by Hao Y1, Huang W, Liao M, Zhu Y, Liu H, Hao C, Liu G, Zhang G, Feng H, Ning X, Li H, Li Z.(PubMed)
(7) Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention by Kowalczyk MC1, Walaszek Z, Kowalczyk P, Kinjo T, Hanausek M, Slaga TJ.(PubMed)
(8) Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects by Banno N1, Akihisa T, Tokuda H, Yasukawa K, Higashihara H, Ukiya M, Watanabe K, Kimura Y, Hasegawa J, Nishino H.(PubMed)
(9) Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention by Kowalczyk MC1, Walaszek Z, Kowalczyk P, Kinjo T, Hanausek M, Slaga TJ.(PubMed)

Tuesday, March 29, 2016

The smoothie of Enrich cow's milk formulas, and Sodium bicarbonate for Prevention and Treatment of Renal Tubular Acidosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Renal Tubular Acidosis
Yield: 2 servings (about 8 ounces each)
2 cups of Enrich cow's milk formulas, 
2.5  grams Sodium bicarbonate

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Renal Tubular Acidosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Renal Tubular Acidosis is a condition in which the kidneys fail to to excrete acids into the urine, leading to acidity in the blood stream.

Recent studies back by well known institutions proposed, Enrich cow's milk formulas, Tomato, Turmeric and Grape Juice may be the next generation of natural ingredients for prevention and treatment of Neonatal Hepatitis.

According to the Children's Hospital, Dortmund, Germany. modified cow milk enriched with sodium and potassium exhibited preventive effect on the rate of development of incipient late metabolic acidosis in premature infants(1).

Sodium bicarbonate, a chemical compound with the formula Na+/HCO3 plays a major role in renal bicarbonate absorption via proximal tubules and therefore is crucial for maintaining normal blood pH(3).
The compound chemical exhibited anti renal tubular acidosis effects involved in stimulus response coupling, cell growth regulation, cell differentiation, and perhaps the progression of nephrosclerosis(2).

According to the study conducted by Dr. R. Curtis Morris Jr. and  Dr.  Anthony Sebastian Alkali Therapy, including sodium bicarbonate may be help in promoted excretion of acid, and normal growth in children, reduced metabolic acidosis induced hypercalciuria and consequent metabolic bone disease and hypercalciuric nephrolithiasis(4).

The effectiveness of Enrich cow's milk formulas, and Sodium bicarbonate may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Renal Tubular Acidosis with little or no adverse effects.

People who are at high risk of Renal Tubular Acidosis due to genetic mutation, .... should drink at least one serving daily and women with Renal Tubular Acidosis should drink no more than 4 servings daily, depending to digestive toleration.


References
(1) Modified cow's milk formula with reduced renal acid load preventing incipient late metabolic acidosis in premature infants by Kalhoff H1, Diekmann L, Hettrich B, Rudloff S, Stock GJ, Manz F.(PubMed)
(2) Light-chain-induced renal tubular acidosis: effect of sodium bicarbonate on sodium-proton exchange by Reusch HP1, Mann JF, Mihatch MJ, Siffert W, Luft FC.(PubMed)
(3) Proximal renal tubular acidosis and ocular pathology: a novel missense mutation in the gene (SLC4A4) forsodium bicarbonate cotransporter protein (NBCe1). by Demirci FY1, Chang MH, Mah TS, Romero MF, Gorin MB.(PubMed)
(4) Alkali Therapy In Renal Tubular Acidosis: Who Needs It? by R. Curtis Morris Jr. and
Anthony Sebastian(JASN)

The Smoothies for Prevention and Treatment of Diabetic Nephropathy back by Renowned Institutions

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Imaging of long term intake of delicious smoothies loved by many with the power of reduced risk and treatment of chronic illness with no one mentions about. In fact, it happens. Epidemiological studies with strong evidences suggested that blueberry oral administration hold a potential with therapeutic values for reduced risk of women who carry the mutation gene and treatment of breast cancer(*).

The curable smoothies are collection of recipes produced from natural sources, including organic fruits and vegetables, and some herbs which have been proven effectively for reduced risk and treatment for diseases and syndromes by scientific research of clinical trials and/or studies.

The finding of foods from natural sources has been a dream of scientists and scholars since ancient time. Socrates Said," Let foods be your medicine and let medicine be your foods". Let all of us all exercise the values of the past wisdom to build a letter living and living health while enjoining these delicious drinks.

Diabetic nephropathy is a form of progressive kidney disease caused by damage to the small veins in the kidneys' glomeruli. According to the Purdue University College of Pharmacy, antihypertensive therapy are recommendations for prevention of nephropathy in diabetic hypertensive patients(**).

The prevention of nephropathy in diabetic hypertensive patients

1. The Smoothie for reduced risk of hypertension 
The smoothie for reduced risk and treatment of  Hypertension

Yield: 2 servings (about 8 ounces each)
3/4 cup celery
3/4 cup of apple with peel
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the celery, apple with peels, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. high blood pressure means raising pressure in your heart. If your blood pressure stays high over time it can damage the body in many ways.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but also induced many irreversible adverse effects, including kidney damage.

Diet rich in fruits and vegetable and reduced intake of red meat, saturated fat and trans fat has shown to attenuated risk of hypertension(1). Recent study showed that celery(2) intake used conjunction with berries(3) and green tea(4) may be the potential drink for prevention and treatment of hypertension.

Celery is a species of Apium graveolens, belongings to the family Apiaceae, cultivated all around the globe as a vegetable. According to Chronic administration of hexanic, methanolic, and aqueous-ethanolic extracts of celery seed effectively exhibited an antihypertensive activity in chronic treatment of elevated BP in tested animals(5).

Dr. Dianat M and the research team at the Ahvaz Jundishapur University of Medical Sciences said," hydro-alcoholic celery leaf extract on systolic blood pressure (SBP), heart rate (HR) and lipid profile in animals' model of hypertension induced by fructose"(6)

3‑n‑butylphthalide (NBP), an phytochemical found in celery seed used in traditional Chinese medicine exhibited significantly antihypertensive and attenuated progression of hypertensive effects through decreased oxidative stress and the expression of pro‑inflammatory cytokines(7).
Apple is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae. It is one of the most widely cultivated tree fruits. With phytochemical flavonoids, apple and its peel inhibited angiotensin converting enzyme (ACE) in promoted the development of high blood pressure, Dr Balasuriya N and Dr. Rupasinghe HP. Suggested(8)According to the Mount Sinai School of Medicine, "Flavonoid (found abundantly in fruits and vegetable)(10) intake has been inversely associated with mortality from coronary heart disease and stroke,..... Lowering blood pressure through increased dietary consumption of dietary antioxidants(such as flavonoid) may decrease the rate of end-organ damage that is secondary to hypertension"(9).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Epigallocatechin-3-O-gallate (EGCG), the main polyphenol presence in green tea is best known for its antioxidant and anti inflammatory effect. In animal model, the phytochemical exhibited anti hypertensive and progressive activity through reduction of oxidative stress in paraventricular nucleus of hypothalamus (PVN), the Xi'an Jiaotong University Health Science Center study showed(11).

Dr. Yarmolinsky J and the research team at the Federal University of Rio Grande do Sul, suggested that, intake of tea are shown to reduce blood pressure in individuals within prehypertensive and hypertensive ranges in the review of all relevant studies published from 1946 to September 27, 2013.(12).

Furthermore, green tea extract (GTE) inhibited the oxidative stress and ingiotensin (Ang) II induces endothelial dysfunction (ED) causes of hypertension through scavenging of superoxide anion generation, the University of Padova, insisted(13).

People who are at increased risk of hypertension due to family history, Diabetic nephropathy,... .....should drink at least one cup daily and people with chronic hypertension should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

2. The smoothie for reduced risk and treatment of diabetes
Yield: 2 servings (about 8 ounces each)

1 3/4 cup whole food papaya
1/4 tsp cinnamon
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)
1. Place whole food papaya, cinnamon and green tea drink in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of diabetes has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases,diabetes is also caused by allergic reactions of cells in the immune system

Cinnamon, a kitchen spicy in many cultures, may have gained many believers, including medical professions because of its anti diabetic effect, through regulating the blood glucose levels in healthy and diabetic subjects. According to herbalists, intake of 1/4 tsp. in the morning and evening may reduce the blood sugar significantly with little or no adverse effects.

The herb has been use in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.(14).

According to the 2011 statistic from National Diabetes InformationClearinghouse (NDIC), among U.S. residents ages 65 years and older, 10.9 million, or 26.9 percent, had diabetes in 2010, about 215,000 people younger than 20 years had diabetes—type 1 or type 2—in the United States in 2010 and approximately, 1.9 million people ages 20 years or older were newly diagnosed with diabetes in 2010 in the United States.

In a total of 66 patients with type 2 diabetes study conducted by Xuhui District Central Hospital, showed a significant reduction of blood triglyceride levels in the low-dose group, after 3 months of oral administration(15)

Some researchers suggested that cinnamon extract may improve fasting blood glucose levels and glucose tolerance without altering the insulin secretion, through lower triglyceride and increased liver glycogen content and improved insulin action in liver tissues(16).

Dr. Kim SH and Dr. Choung SY. told PubMed "The effect of cinnamon in significantly increases insulin sensitivity, reduces serum, and hepatic lipids, and improves hyperglycemia and hyperlipidemia possibly by regulating the PPAR(in regulation of metabolism (carbohydrate, lipid, protein))-medicated glucose and lipid metabolism"(17)

In support of the above, chromium(Cr) and polyphenols found in cinnamon(Cinnamomon cassia) indicated a improvement of glucose, insulin, cholesterol and HbA1c(Glucose lab test) in patients with type 2 diabetesfollowing Cr supplementation, in a double-blind placebo-controlled study(20).

Unfortunately, according to the Western University of Health Sciences, consumption of cinnamon is associated with a statistically significant decrease in levels of fasting plasma glucose, but insisted that high degree of heterogeneity may limit the ability to apply these results to patient care, due to the unclear preferred dose and duration of therapy(18)

A randomized clinical trial in which 70 Patients with type II diabetesassigned randomly two groups (35 in cinnamon and 35 in placebo group for the testing of the effect of cinnamon on the glucose level in blood, indicated an insignificant effect of using cinnamon on glucose level of diabetic patients and the herb should not be recommended to patients with type II diabetes depending on further studies(19).


People with Type II Diabetes may also be thinking to add whole food papaya into their diet. the recent study suggested(20) ,
The finding not only showed the effectiveness of unripe pawpaw fruit (Carica papaya) in inhibition α-amylase, α-glucosidase, but also induced lipid peroxidation in a dose-dependent manner, in rat pancreas(20).
The key enzymes of α-amylase, α-glucosidase, involved in the digestion of carbohydrates, have been linked to onset of type 2 diabetes. Inhibition of these enzymes can significantly reduce the post-prandial increase of blood glucose and have been considered by therapists in use for management of blood glucose level in type 2 diabetic and borderline patients(21).

In streptozotocin-induced diabetic rats study, the aqueous extract of leaves of C. papaya administered strongly controlled blood glucose levels(22), through prevention of hepatocyte disruption, as well as accumulation of glycogen and lipids via its hypoglycemic and antioxidant effect(23)


In a new study, conducted by the researchers at the Davis Heart and Lung Research Institute, fermented papaya preparation was tested whether it improves dermal wound healing outcomes in adult diabetic mice by preventing the risk of infections(24).
The result was astonishing, the fermentation not only up regulated the Sp1 DNA binding activity(modulating the cellular response to DNA damage) in Peripheral blood mononuclear cells (PBMC) but also the protein and mRNA expression of Rac2(regulates a number of cellular functions)(24).

A randomized controlled clinical trial conducted at the Cardiac Centre, ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of Biosciences University of Mauritius, suggested that oral administration of 6g FPP®/day for a period of 14 weeks could improve the general health status of several organs targeted by oxidative stress duringdiabetes and suggested that the supplement may be used in the management the complications of diabetes such as cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(25).
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Green tea has ling been known for its effect on treatment of diabetes in ancient Chinese literature, probably due to green tea phytochemical polyphenols(26).Dr. Solayman M and the research tea at the Universiti Sains Malaysia said, "Natural products containing high polyphenol levels can control carbohydrate metabolism by various mechanisms, such as protecting and restoring beta-cell integrity, enhancing insulin releasing activity, and increasing cellular glucose uptake"(27).

In a total of 17,413 persons (6727 men and 10,686 women; 49% of the original study population) who were 40 to 65 years of age, daily drinking of green tea reduced risk of diabetes by 33%, especially in women and in overweight men(13).Furthermore, intake of green tea of 150 ml green tea, three times a day for four weeks, has positive effect on insulin resistance and certain lipoproteins in type 2 DM, according to the Shahid Sadoughi University of Medical Science(28).

People who are at increased risk of diabetes due to family history, gene mutation, obesity, Diabetic nephropathy, ....should drink at least one serving daily and people with diabetes should drink no more than 4 servings a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(**) Antihypertensive therapy for the prevention of nephropathy in diabetic hypertensive patients by Isaacs AN1,2, Vincent A1,3.(PubMed)
(1) Fruit and Vegetable Consumption and the Incidence of Hypertension in Three Prospective Cohort Studies by Borgi L1, Muraki I2, Satija A2, Willett WC2, Rimm EB2, Forman JP2.(PubMed)
(2) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(3) Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors by Toh JY1, Tan VM, Lim PC, Lim ST, Chong MF.(PubMed)
(4) Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome by Ihm SH1, Jang SW, Kim OR, Chang K, Oak MH, Lee JO, Lim DY, Kim JH.(PubMed)
(5) Antihypertensive effect of celery seed on rat blood pressure in chronic administration by Moghadam MH1, Imenshahidi M, Mohajeri SA.(PubMed)
(6) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(7) Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats by Zhu J1, Zhang Y1, Yang C1.(PubMed)
(8) Antihypertensive properties of flavonoid-rich apple peel extract by Balasuriya N1, Rupasinghe HP.(PubMed)
(9) Dietary flavonoids and hypertension: is there a link? by Moline J1, Bukharovich IF, Wolff MS, Phillips R.(PubMed)
(10) Antihypertensive effects of the flavonoid quercetin by Perez-Vizcaino F1, Duarte J, Jimenez R, Santos-Buelga C, Osuna A.(PubMed)
(11) Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension by Yi QY1, Qi J, Yu XJ, Li HB, Zhang Y, Su Q, Shi T, Zhang DM, Guo J, Feng ZP, Wang ML, Zhu GQ, Liu JJ, Shi XL, Kang YM.(PubMed)
(12) Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials by Yarmolinsky J1, Gon G2, Edwards P2.(PubMed)
(13) Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts by Antonello M1, Montemurro D, Bolognesi M, Di Pascoli M, Piva A, Grego F, Sticchi D, Giuliani L, Garbisa S, Rossi GP.(PubMed)
(14) @Popular Herbs -Cinnamon
(15) Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes by Lu T, Sheng H, Wu J, Cheng Y, Zhu J, Chen Y.(PubMed)
(16) Cinnamon extract improves insulin sensitivity in the brain and lowers liver fat in mouse models of obesity by Sartorius T1, Peter A2, Schulz N3, Drescher A2, Bergheim I4, Machann J5, Schick F6, Siegel-Axel D2, Schürmann A3, Weigert C1, Häring HU1, Hennige AM(PubMed)
(17) Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice by Kim SH1, Choung SY.(PubMed)
(18) Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis by Allen RW1, Schwartzman E, Baker WL, Coleman CI, Phung OJ.(PubMed)
(19) The Effect of Cinnamon on Glucose of Type II Diabetes Patients by Hasanzade F1, Toliat M2, Emami SA3, Emamimoghaadam Z(PubMed)(7) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya) by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO.(PubMed)
(20) Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update by Tundis R1, Loizzo MR, Menichini F.(PubMed)
(21) Antihyperglycemic and hypolipidemic activities of aqueous extract ofCarica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y, Bhixavatimath P.(PubMed)
(22) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(23) Correction of aberrant NADPH oxidase activity in blood-derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation by Dickerson R1, Deshpande B, Gnyawali U, Lynch D, Gordillo GM, Schuster D, Osei K, Roy S.(PubMed)
(24) Effects of a short term supplementation of a fermented papaya preparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)
(25) The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults by Iso H1, Date C, Wakai K, Fukui M, Tamakoshi A; JACC Study Group(PubMed)
(26) Polyphenols: Potential Future Arsenals in the Treatment of Diabetes by Solayman M, Ali Y, Alam F, Islam MA, Alam N, Khalil MI, Gan SH1(PubMed)
(27) Polyphenols: Potential Future Arsenals in the Treatment of Diabetes by Solayman M, Ali Y, Alam F, Islam MA, Alam N, Khalil MI, Gan SH1.(PubMed)
(28) The Effect of Green Tea versus Sour Tea on Insulin Resistance, Lipids Profiles and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial by Mozaffari-Khosravi H1, Ahadi Z1, Fallah Tafti M2.(PubMed)

Monday, March 28, 2016

The Smoothie of Green tea, Orange and Grape for Prevention and Treatment of Renal Amyloidosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Renal Amyloidosis  
Yield: 2 servings (about 8 ounces each)

1/2 cup orange
1 cup grape
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Renal Amyloidosis  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Green tea, Orange and Grape may be the next generation of natural ingredients for prevention and treatment of Reno Amyloidosis. 

 Renal Amyloidosis is a condition of kidney damage caused by deposited of amyloid, affecting kidney function in filtering wastes and breaking down proteins. According to the joint study led by the Tokushima University Graduate School, (-)-epigallocatechin-3-gallate (EGCG), a tea-derived flavanol, expressed anti Reno Amyloidosis effects by inhibited fibril formation and disaggregated fibrils preformed(1).
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. An observational study, suggested, green tea consumption is associated to amyloid fibril reduction, due to its (-)-epigallocatechin-3-gallate (EGCG) in significant decrease of left ventricular (LV) myocardial mass through stabilization of wild-type transthyretin amyloid cardiomyopathy (wtATTR-CM)(2).
Furthermore, the phytochemical isolated from green tea also inhibited the progression of Reno Amyloidosis by modulating the rate of formation and structural properties of apolipoprotein C-II amyloid fibrils, the The University of Melbourne, Parkville insisted(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry also inhibited the process of amyloid formation by the normally soluble hormone islet amyloid polypeptide (IAPP) which contributed to β-cell death in type 2 diabetes, according to the Stony Brook University(4).

Vitamin C, one of the powerful may benefit patients with amyloidosis, through its free radical scavenger activity(5). 
According to Dr. Ravid M and colleagues, in animal model, ascorbic acid partially restored the amyloid-degrading activity in dose-dependent manner(6).

The effectiveness of  Green tea, Orange and Grape may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Renal Amyloidosis with little or no adverse effects.

People who are at high risk of Renal Amyloidosis due to aging, weaken reno function... should drink at least one serving daily and women with Renal Amyloidosis  should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.


References
(1) The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity by Nakajima H1,2, Nishitsuji K1, Kawashima H3, Kuwabara K1,2, Mikawa S2, Uchimura K4, Akaji K3, Kashiwada Y5, Kobayashi N6, Saito H2,Sakashita N1.(PubMed)
(2) Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study by Siepen FA1, Bauer R1, Aurich M1, Buss SJ1, Steen H1, Altland K2, Katus HA1, Kristen AV1(PubMed)
(3) Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils by Zlatic CO1, Mao Y1, Ryan TM1, Mok YF1, Roberts BR1, Howlett GJ1, Griffin MD1.(PubMed)
(4) Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions by Tu LH1, Young LM, Wong AG, Ashcroft AE, Radford SE, Raleigh DP.(PubMed)
(6) Ascorbic acid-induced regression of amyloidosis in experimental animals by Ravid M, Chen B, Bernheim J, Kedar I.(PubMed)

Sunday, March 27, 2016

The Smoothie of Cooked Tomato, broccoli and Orange Juice for Prevention and Treatment of Hyperalbuminemia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Hyperalbuminuria 
Yield: 2 servings (about 8 ounces each)
1 1/4 cups tomato
1/2 cup broccoli
1 cup organic orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Albuminuria  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Cooked Tomato, broccoli and Orange Juice may be the next generation of natural ingredients for prevention and treatment of Albuminuria due to kidney decline

Albuminuria is a medical condition with too much protein in the urine, found
typically inpatients with kidney diseases. According to the Brigham and Women's Hwayospital, higher derivative vitamin A, beta-carotene, intake may reduce risk for Glomerular Filtration Rate (GFR) decline(1).

Lycopene, a chemically a carotene, also exhibited anti nephrotoxicity through anti proinflammatory pathways(3),

Coenzyme Q10, antioxidant found abundantly in broccoli may prevent or minimize cyclosporine nephrotoxicity through its antioxidant effect(4).
Dr. Ishikawa A and Dr. Homma Y. professors a the the University of Tokyo said, "Ubiquinol, the reduced form of coenzyme Q10 ......an antioxidants, may have potential for preventing CyA nephrotoxicity"(5).
In type 2 diabetes model, intake of supplement of coenzyme Q10 exhibited anti renal mitochondrial dysfunction caused by diabetic induced nephropathy(6).

Free radical scavengers vitamin C (Orange)  intake, increased plasma and renal cortical vitamin C or E content in prevention of renal injury(7) and development of diabetic nephropathy(9).
According to the Yonsei University Wonju College of Medicine, vitamin C exhibited anti oxidative stress in ameliorated albuminuria and renal sclerosis in experimental diabetic rats(8).

The effectiveness of Cooked Tomato, broccoli and Orange Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Albuminuria with little or no adverse effects.

People who are at high risk of Albuminuria due to aging, weaken renal function... should drink at least one serving daily and women with Albuminuria should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary as overweight and obesity are well-established risk factors for cardiovascular disease and declined kidney function(2) 


References
(1) Associations of diet with albuminuria and kidney function decline. by Lin J1, Hu FB, Curhan GC.(PubMed)
(2) Association between body mass index and CKD in apparently healthy men by Gelber RP1, Kurth T, Kausz AT, Manson JE, Buring JE, Levey AS, Gaziano JM.(PubMed)
(3) Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene. Sahin K1, Tuzcu M, Sahin N, Ali S, Kucuk O.(PubMed)
(4) Effect of reduced form of coenzyme Q10 on cyclosporine nephrotoxicity by Sato T1, Ishikawa A, Homma Y.(PubMed)
(5) Beneficial effect of ubiquinol, the reduced form of coenzyme Q10, on cyclosporine nephrotoxicity by Ishikawa A1, Homma Y.(PubMed)
(6) Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes by Sourris KC1, Harcourt BE, Tang PH, Morley AL, Huynh K, Penfold SA, Coughlan MT, Cooper ME, Nguyen TV, Ritchie RH, Forbes JM.(PubMed)
(7) Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-beta, and glomerular size in diabetes by Craven PA1, DeRubertis FR, Kagan VE, Melhem M, Studer RK.(PubMed)
(8) Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats by Lee EY1, Lee MY, Hong SW, Chung CH, Hong SY.(PubMed)
(9) Effect of vitamin E and vitamin C supplementation on antioxidative state and renal glomerular basement membrane thickness in diabetic kidney by Kedziora-Kornatowska K1, Szram S, Kornatowski T, Szadujkis-Szadurski L, Kedziora J, Bartosz G.(PubMed)

Saturday, March 26, 2016

The Fabulous Smoothie of Green Tea, Blueberry and Mango for Prevention and Treatment of Stomach Cancer/Gastric Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Stomach Cancer/Gastric Cancer
Yield: 2 serving (about 8 ounce each)
1 cup blueberry
1/2 cup mango
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Stomach Cancer/Gastric Cancer has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Stomach cancer is defined as condition of abnormal growth of the mucus-producing cells of the inside lining of the stomach. Adenocarcinoma is the most common type of stomach cancer.

Recent studies back by renowned institutions, conveyed that green tea(1), blueberry(4) and mango(7) may be holding a key for extracting natural ingredient for reduced early onset and treatment of Stomach Cancer/Gastric Cancer. According to the Sichuan University, regular green tea consumption is associated to a minor inverse association of risk of gastric cancer in all population-based case-control studies(1).
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects,
green tea now has been cultivated all over the world in suitable climate.
The University of Utah School of Medicine study propose the prevention effects of green tea against the early onset of cancers overall(2).
In fact, the conflict results between green tea intake and gastric cancer risk may be due to how the drink was served in temperature wise. One study had shown a significantly lowered GC risk when tea was served warm to cold. Another study also showed a significantly risk with lukewarm tea(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape is also associated to reduce risk of gastric cancer, according to the Cook County Hospital(4).
Dr. Riles WL and colleagues in the investigation of the resveratrol effect against gastric cancer, indicated that the antioxidant up regulating cancer suppressive gene p53 in in SNU-1 and AGS cancer cell lines in different mechanisms(5).
Other study suggested the effectiveness of resveratrol for treatment of gastric cancer probable through intracellular signaling in growth arrest and apoptosis against tumor progression(6).

Gallic acid is a phytochemical in the class of Phenolic acids, found abundantly in mango and strawberries also inhibited gastric cancer cell lines through inhibition of NF-κB, the pro inflammatory cytokines activity(7), in immunoreactivity assay of cytoskeletal F-actin(8).
Dr. Yoshioka K and researchers at the Mie University, suggested, in human stomach cancer KATO III cells, gallic acid exhibited anti the KATO III cell line through induction of apoptosis in concentration- and time-dependen(9).

The finding of the effectiveness of Green Tea, Blueberry and Mango may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of  Stomach Cancer/Gastric Cancer 

People who are at increased risk of Stomach Cancer/Gastric Cancer , due to family history, auto immunity,....should drink the juices at least one a day. People with Stomach Cancer/Gastric Cancer   should drink the juice as much as  as they can depending to digestive toleration.
Life style and diet pattern change are recommended.



References
(1) Green tea and gastric cancer risk: meta-analysis of epidemiologic studies by Zhou Y1, Li N, Zhuang W, Liu G, Wu T, Yao X, Du L, Wei M, Wu X(PubMed)
(2) Coffee, tea, caffeine intake, and the risk of cancer in the PLCO cohort by Hashibe M1,2, Galeone C3, Buys SS4, Gren L1, Boffetta P5, Zhang ZF6, La Vecchia C7.(PubMed)
(3) Green tea and the risk of gastric cancer: epidemiological evidence by Hou IC, Amarnani S, Chong MT, Bishayee A.(PubMed)
(4) Resveratrol regulates cellular PKC alpha and delta to inhibit growth and induce apoptosis in gastric cancer cells by Atten MJ1, Godoy-Romero E, Attar BM, Milson T, Zopel M, Holian O.(PubMed)
(5) Resveratrol engages selective apoptotic signals in gastric adenocarcinoma cells by Riles WL1, Erickson J, Nayyar S, Atten MJ, Attar BM, Holian O.(PubMed)
(6) Resveratrol: A potential challenger against gastric cancer by Zulueta A1, Caretti A1, Signorelli P1, Ghidoni R1.(PubMed)
(7) Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition of NF-κB activity by Ho HH1, Chang CS, Ho WC, Liao SY, Lin WL, Wang CJ.(PubMed)
(8) Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-kappaB activity and downregulation of PI3K/AKT/small GTPase signals by Ho HH1, Chang CS, Ho WC, Liao SY, Wu CH, Wang CJ.(PubMed)
(9) Induction of apoptosis by gallic acid in human stomach cancer KATO III and colon adenocarcinoma COLO 205 cell lines by Yoshioka K1, Kataoka T, Hayashi T, Hasegawa M, Ishi Y, Hibasami H.(PubMed)

The Curable Smoothie of Green Tea, Cinnamon and Strawberry for Prevention and Treatment of Scabies

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  scabies
Yield: 2 servings (about 8 ounces each)
1 1/2 cups blueberry
1 tsp cinnamon
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of scabies  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Scabies is an itchy, highly contagious skin infestation caused by the mite Sarcoptes scabiei, accompanied with glomerulonephritis and rheumatic fever.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years used in traditional Chinese medicine for treatment of variety of diseases, including cancers and heart diseases. According to the Taiyo Kagaku Co. Ltd, green tea polyphenols are effective in inhibited development and growth of bacterial spores in tested Bacillus bacteria(1).
Epidemiologically, green tea catechins exhibited antimicrobial effects against various pathogenic bacteria, including Escherichia coli(2), Propionibacterium Acnes, Propionibacterium Granulosum, Staphylococcus Aureus and Staphylococcus Epidermidis(3)

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belongings to the family Lauraceae. The spice also processed anti microbial effect against many types of bacteria, including Listeria monocytogenes Scott A(4), L. monocytogenes, S. enterica(5), Escherichia coli and Staphylococcus aureus(6).

Strawberries is a genius of Fragaria × ananassa belongs to the family Roseaceae, grown all over the world with suitable climate for commercial profits and for health benefits.Its aqueous extracts exhibited anti microbial effect against the expression of the virulence factors of Vibrio cholerae strains(7), Staphylococcus bacteria. Salmonella bacteria(8).

Taking altogether, The combination of Green Tea, Cinnamon and Strawberry may offer the potential effect in prevention of the onset and treatment of Scabies, through their anti bacterial effect.
 People who are at increased risk of Scabies are wise to drink at least one serving daily. People with  Scabies, should drink the juice as much as they can, depending to the toleration of digestive system.


References
(1) Antimicrobial effects of green tea polyphenols on thermophilic spore-forming bacteria by Sakanaka S1, Juneja LR, Taniguchi M.(PubMed)
(2) Effects of green tea on Escherichia coli as a uropathogen. by Noormandi A1, Dabaghzadeh F1.(PubMed)
(3) Antimicrobial Activity of Pomegranate and Green Tea Extract on Propionibacterium Acnes, Propionibacterium Granulosum, Staphylococcus Aureus and Staphylococcus Epidermidis by Li Z, Summanen PH, Downes J, Corbett K, Komoriya T, Henning SM, Kim J, Finegold SM.(PubMed))
(4) Antimicrobial activity of clove and cinnamon essential oils against Listeria monocytogenes in pasteurized milk by Cava R1, Nowak E, Taboada A, Marin-Iniesta F.(PubMed)
(5) Effects of allspice, cinnamon, and clove bud essential oils in edible apple films on physical properties and antimicrobial activities by Du WX1, Olsen CW, Avena-Bustillos RJ, McHugh TH, Levin CE, Friedman M.(PubMed)
(6) Fabrication of electrospun polylactic acid nanofilm incorporating cinnamon essential oil/β-cyclodextrin inclusion complex for antimicrobial packaging by Wen P1, Zhu DH1, Feng K2, Liu FJ2, Lou WY2, Li N2, Zong MH3, Wu H4.(PubMed)
(7) Antimicrobial Effects of Blueberry, Raspberry, and Strawberry Aqueous Extracts and theirEffects on Virulence Gene Expression in Vibrio cholerae.by Khalifa HO1,2, Kamimoto M1, Shimamoto T1, Shimamoto T1.(PubMed)
(8) Berry phenolics selectively inhibit the growth of intestinal pathogens by Puupponen-Pimiä R1, Nohynek L, Hartmann-Schmidlin S, Kähkönen M, Heinonen M, Määttä-Riihinen K, Oksman-Caldentey KM.(PubMed)

Friday, March 25, 2016

The Smoothie of Tomato, Blueberry and Green tea drink for reduced Risk and Treatment of Amyloid diseases (primary amyloidosis)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Amyloid diseases
Yield: 2 servings (about 8 ounces each)

1/2 cup tomato
1 cup blueberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Amyloid diseases has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.
Amyloid diseases is a condition of abnormal proteins build up in the body tissues and organs.

Recent studies back by well known institutions proposed, Tomato, Blueberry and Green tea drink may be the next generation of natural ingredients for prevention and treatment of Amyloid diseases.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world. According to joint study led by the Tokushima University Graduate School, polyphenol (-)-epigallocatechin-3-gallate inhibited amyloid fibril formation of various amyloidogenic proteins in induction of cytotoxicity(1). The antioxidant also impeded the amyloid fibrils formed by proteolytic fragments of prostatic acid phosphatase, through its anti-viral properties(2).
Dr. Zlatic CO. and colleagues at the The University of Melbourne, in the investigation of Epigallocatechin Gallate effect against protein misfolding and aggregation, leading to amyloid fibril formation, said, "EGCG significantly altered the size distribution of fibrils, most likely by promoting the lateral association of fibrils and subsequent formation of large aggregates"(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry may also benefits patients with Amyloid diseases through inhibition of amyloid formation by islet amyloid polypeptide(4). On damages of mouse cortical neurons resveratrol exhibited neuro protective effects through SIRT1/Akt1 neuroprotective pathway in tumorigenesis via increased cell viability and reduced the number of apoptotic cells(5).
Dr. Granzotto A and Dr. Zatta P said, "resveratrol (May be) a neuroprotectant in dementia in relation to the oxidative stress produced by amyloid and metal dysmetabolism"(6).

Carotenoids, an derivative of vitamin A found abundantly in tomato also expressed significantly anti degenerative diseases mediated by oxidative stress induced amyloids deposition and fibril formation(7) in patients with Alzheimer's Disease (AD). 
Lycopene, a member of arotenoids also protected mitochondria against Aβ-induced damages against neurotoxicity by inhibiting mitochondrial oxidative stress and improving mitochondrial function, according to study led by the Center for Diseases Prevention and Control of the Rocket Force of PLA(8).

The effectiveness of  Green tea, Tomato and Blueberry may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Amyloid diseases (primary amyloidosis)  with little or no adverse effects.

People who are at high risk of Amyloid diseases (primary amyloidosis)  due to aging, weaken reno function... should drink at least one serving daily and women with Amyloid diseases (primary amyloidosis)  should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.



References
(1) The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity by Nakajima H1,2, Nishitsuji K1, Kawashima H3, Kuwabara K1,2, Mikawa S2, Uchimura K4, Akaji K3, Kashiwada Y5, Kobayashi N6, Saito H2, Sakashita N1.(PubMed)
(2) Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107), and SEM2(49-107) seminal amyloid fibrils by Castellano LM1, Hammond RM2, Holmes VM3, Weissman D3, Shorter J4.(PubMed)
(3) Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils by Zlatic CO1, Mao Y1, Ryan TM1, Mok YF1, Roberts BR1, Howlett GJ1, Griffin MD1.(PubMed)
(4) Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions by Tu LH1, Young LM, Wong AG, Ashcroft AE, Radford SE, Raleigh DP.(PubMed)
(5) Neuroprotective effects of resveratrol on damages of mouse cortical neurons induced by β-amyloid through activation of SIRT1/Akt1 pathway by Zhang J1, Feng X, Wu J, Xu H, Li G, Zhu D, Yue Q, Liu H, Zhang Y, Sun D, Wang H, Sun J.(PubMed)
(6) Resveratrol and Alzheimer's disease: message in a bottle on red wine and cognition by Granzotto A1, Zatta P2.(PubMed)
(7) Carotenoids and Alzheimer's disease: an insight into therapeutic role of retinoids in animal models by Obulesu M1, Dowlathabad MR, Bramhachari PV.(PubMed)