Natural Medicine for Fatty Liver And Obesity Reversal
Thursday, December 22, 2011
Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health
In the studies of "Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys" by Wood CE, Register TC, Cline JM., posted in US National Library of Medicine National Institutes of Health, researchers found that long-term exposure to soy isoflavonoids, equol in particular, may facilitate endogenous estrogen clearance and catabolism to more benign 2-hydroxylated metabolites.
In the study of "Effects of soybean glyceollins and estradiol in postmenopausal female monkeys" by Wood CE, Clarkson TB, Appt SE, Franke AA, Boue SM, Burow ME, McCoy T, Cline JM., posted in US National Library of Medicine National Institutes of Health, researchers found that soybean glyceollins are natural compounds with potential estrogen-modulating properties in the breast.
Om the studies of "Glyceollin-elicited soy protein consumption induces distinct transcriptional effects compared to standard soy protein" by Wood CE, Boue SM, Collins-Burow BM, Rhodes LV, Register TC, Cline JM, Dewi FN, Burow ME., posted in US National Library of Medicine National Institutes of Health, researchers found that The GLY diet also resulted in lower serum total cholesterol, specifically non-high-density lipoprotein cholesterol, and increased serum triglycerides compared to the C/L diet. No effects of GLY or SOY were seen on serum insulin, adipocytokines, or vascular and bone turnover markers. These preliminary findings suggest that glyceollin-enriched soy protein has divergent effects from standard soy with some specificity for adipocyte activity and nutrient metabolism.
In the study of "Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen" by Ide H, Tokiwa S, Sakamaki K, Nishio K, Isotani S, Muto S, Hama T, Masuda H, Horie S., posted in US National Library of Medicine National Institutes of Health, researchers found that isoflavones and curcumin could modulate serum PSA levels. Curcumin presumably synergizes with isoflavones to suppress PSA production in prostate cells through the anti-androgen effects.
In the study of "Isoflavone intake and risk of lung cancer: a prospective cohort study in Japan"by Shimazu T, Inoue M, Sasazuki S, Iwasaki M, Sawada N, Yamaji T, Tsugane S; Japan Public Health Center-based Prospective Study Group., posted in US National Library of Medicine National Institutes of Health, researchers found that During 11 y (671,864 person-years) of follow-up, we documented 481 male and 178 female lung cancer cases. In men we found an inverse association between isoflavone intake and risk of lung cancer in never smokers (n = 13,051; multivariate HR in the highest compared with the lowest quartile of isoflavone intake: 0.43; 95% CI: 0.21, 0.90; P for trend = 0.024) but not in current or past smokers. A similar, nonsignificant inverse association was seen in never-smoking women (n = 38,211; HR: 0.67; 95% CI: 0.41, 1.10; P for trend = 0.135). We also tested effect modification by smoking status (P for interaction = 0.085 in men and 0.055 in men and women combined) and concluded that in a large-scale, population-based, prospective study in Japan, isoflavone intake was associated with a decreased risk of lung cancer in never smokers
Saturday, December 17, 2011
- 3 tablespoons peanut oil
- 1 pound firm tofu, cubed
- 1 red onion, sliced
- 1 red bell pepper, sliced
- 1 green chile pepper, chopped
- 3 cloves garlic, crushed
- 1/3 cup hot water
- 3 tablespoons white vinegar
- 3 tablespoons soy sauce
- 1 tablespoon brown sugar
- 1 teaspoon cornstarch
- 1 teaspoon crushed red pepper flakes
- Heat peanut oil in a wok or large frying pan over medium-high heat. Toss the tofu into the oil, and cook until browned on all sides. Once browned, toss in onion, bell pepper, chile pepper, and garlic; cook until just tender, about 5 minutes.
- In a small bowl, whisk together the hot water, vinegar, soy sauce, brown sugar, cornstarch, and red pepper flakes. Pour over tofu and vegetables, toss to coat, and simmer 3 to 5 minutes, or until sauce thickens slightly.
8 Hrs 35 Min
- 1 (16 ounce) package extra firm tofu
- 3 tablespoons olive oil
- 1 egg white
- 1 tablespoon barbeque sauce
- 1 cup all-purpose flour
- 1 teaspoon salt
- 1/2 teaspoon pepper
- 1 cup barbeque sauce
- Drain tofu, and slice into strips. Place in a plastic bag or container, and freeze overnight. This will give the tofu a meatier texture. Thaw tofu strips, and blot with paper towels to dry.
- Heat olive oil in a large skillet over medium heat. In a small bowl, whisk together the egg white and 1 tablespoon of barbeque sauce. Combine the flour, salt, and pepper in a separate bowl. Dip the tofu slices into the egg mixture, then into the flour mixture, shaking off excess flour. Fry in the hot oil for about 1 minute on each side, until golden brown. Just fry enough at one time so they are not crowded. Remove from the oil to paper towels to drain and cool.
- Preheat the oven's broiler. Brush tofu slices with additional barbeque sauce, and allow to marinate while the broiler heats up. Arrange them on a broiler pan, or wire rack set over a cookie sheet for best results.
- Position the oven rack about 6 inches from the heat source. Broil for 5 minutes on each side, or until browned and crisp, watching closely so as not to burn them. Serve warm with the remaining barbeque sauce for dipping.
- Editor's Note
- The nutrition data for this recipe includes the full amount of the breading ingredients. The actual amount of the breading consumed will vary.
- 2 bunches green onions
- 1 (14 ounce) can light coconut milk
- 1/4 cup soy sauce, divided
- 1/2 teaspoon brown sugar
- 1 1/2 teaspoons curry powder
- 1 teaspoon minced fresh ginger
- 2 teaspoons chile paste
- 1 pound firm tofu, cut into 3/4 inch cubes
- 4 roma (plum) tomatoes, chopped
- 1 yellow bell pepper, thinly sliced
- 4 ounces fresh mushrooms, chopped
- 1/4 cup chopped fresh basil
- 4 cups chopped bok choy
- salt to taste
- Remove white parts of green onions, and finely chop. Chop greens into 2 inch pieces.
- In a large heavy skillet over medium heat, mix coconut milk, 3 tablespoons soy sauce, brown sugar, curry powder, ginger, and chile paste. Bring to a boil.
- Stir tofu, tomatoes, yellow pepper, mushrooms, and finely chopped green onions into the skillet. Cover, and cook 5 minutes, stirring occasionally. Mix in basil and bok choy. Season with salt and remaining soy sauce. Continue cooking 5 minutes, or until vegetables are tender but crisp. Garnish with remaining green onion.
- 1/2 cup seasoned bread crumbs
- 5 tablespoons grated Parmesan cheese
- 2 teaspoons dried oregano, divided
- salt to taste
- ground black pepper to taste
- 1 (12 ounce) package firm tofu
- 2 tablespoons olive oil
- 1 (8 ounce) can tomato sauce
- 1/2 teaspoon dried basil
- 1 clove garlic, minced
- 4 ounces shredded mozzarella cheese
- In a small bowl, combine bread crumbs, 2 tablespoons Parmesan cheese, 1 teaspoon oregano, salt, and black pepper.
- Slice tofu into 1/4 inch thick slices, and place in bowl of cold water. One at a time, press tofu slices into crumb mixture, turning to coat all sides.
- Heat oil in a medium skillet over medium heat. Cook tofu slices until crisp on one side. Drizzle with a bit more olive oil, turn, and brown on the other side.
- Combine tomato sauce, basil, garlic, and remaining oregano. Place a thin layer of sauce in an 8 inch square baking pan. Arrange tofu slices in the pan. Spoon remaining sauce over tofu. Top with shredded mozzarella and remaining 3 tablespoons Parmesan.
- Bake at 400 degrees F (205 degrees C) for 20 minutes.
Prep Time: 3 Min
Cook Time: 2 Min
Ready In: 5 Min
- 2 (10 inch) whole wheat tortillas
- 1 (7.5 ounce) package hickory flavor baked tofu
- 1/2 cup shredded sharp Cheddar cheese
- 1 cup fresh baby spinach
- 1 tablespoon Ranch dressing
- 1 tablespoon grated Parmesan cheese, or to taste
- Place the tortillas side by side on a paper plate. Slice tofu, and place slices down the center of each tortilla. Sprinkle cheese over the tofu. Cover with a damp paper towel, and heat in the microwave for about 45 seconds, or until cheese is melted.
- Pile some spinach onto each tortilla, and pour on some Ranch dressing. Sprinkle with Parmesan cheese, roll tortillas around the filling, and eat.
Monday, December 12, 2011
In the study of "Positive regulation of hepatic carnitine palmitoyl transferase 1A (CPT1A) activities by soy isoflavones and L-carnitine" by Shin ES, Cho SY, Lee EH, Lee SJ, Chang IS, Lee TR, posted in US National Library of Medicine National Institutes of Health, found that Genistein and daidzein can up-regulate CPT1A enzyme activity through up-regulation of CPT1A transcription. Co-treatment of L-carnitine and genistein additively increases CPT1A enzyme activity in HepG2 cells. A stable Huh7 cell line transfected with the CPT1A promoter luciferase reporter gene was established and characterized.
In the study of "Individual and combined soy isoflavones exert differential effects on metastatic cancer progression" by Martínez-Montemayor MM, Otero-Franqui E, Martinez J, De La Mota-Peynado A, Cubano LA, Dharmawardhane S., posted in US National Library of Medicine National Institutes of Health, found that differential regulation of Rho GTPases, initiation factors, and survivin may account for the disparate responses of breast cancers to genistein and daidzein diets. This study indicates that consumption of soy foods may increase metastasis.
In the study of "Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells" by Hsu A, Bray TM, Helferich WG, Doerge DR, Ho E., posted in US National Library of Medicine National Institutes of Health, found that the induction of apoptosis was independent of the NF kappaB pathway. Food products that bear a combination of active compounds may be more efficacious and safer as chemo-preventive agents than individual compounds. This 'whole-food'-based approach is significant for the development of public health recommendations for prostate cancer prevention.
In the study of "Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen" by Ide H, Tokiwa S, Sakamaki K, Nishio K, Isotani S, Muto S, Hama T, Masuda H, Horie S. posted in US National Library of Medicine National Institutes of Health, found that isoflavones and curcumin could modulate serum PSA levels. Curcumin presumably synergizes with isoflavones to suppress PSA production in prostate cells through the anti-androgen effects.
Thursday, December 8, 2011
In the study of "Soy protein and isoflavone effects on vasomotor symptoms in peri- and postmenopausal women: the Soy Estrogen Alternative Study" by Burke GL, Legault C, Anthony M, Bland DR, Morgan TM, Naughton MJ, Leggett K, Washburn SA, Vitolins MZ., posted in US National Library of Medicine National Institutes of Health, found that soy protein containing 42 or 58 mg of isoflavones is no more effective than isoflavone-extracted soy protein for improving the number and severity of vasomotor symptoms in peri- and postmenopausal women.
In the study of "Soy extracts versus hormone therapy for reduction of menopausal hot flushes: indirect comparison" by Bolaños-Díaz R, Zavala-Gonzales JC, Mezones-Holguín E, Francia-Romero J., posted in US National Library of Medicine National Institutes of Health, found that HT and soy interventions showed a significant difference in efficacy for the reduction of hot flushes in postmenopausal women when each treatment was compared with placebo. However, using indirect comparison, there is a statistically significant difference between HT and soy extracts in their effects on hot flushes.
In the study of "Soy isoflavones: are they useful in menopause?" by Vincent A, Fitzpatrick LA., posted in US National Library of Medicine National Institutes of Health, found that soy isoflavones are biologically active compounds. Current data are insufficient to draw definitive conclusions regarding the use of isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women. Although epidemiological and basic laboratory studies allude to the possible protective effects of soy isoflavones at specific target tissues.
In the study of "Effects of phytoestrogens derived from soy bean on expression of adhesion molecules on HUVEC" by de Andrade CM, de S MF, Toloi MR., posted in US National Library of Medicine National Institutes of Health, found that Isoflavones extracted from Glycine max soy bean, in vitro, presented antiatherogenic effects, reducing the expression of adhesion molecules and acting as preventive agents as well as therapeutic agents.
In the study of "Puerarin prevents isoprenaline-induced myocardial fibrosis in mice by reduction of myocardial TGF-β1 expression" by Chen R, Xue J, Xie M., posted in US National Library of Medicine National Institutes of Health, found that that puerarin ( the main isoflavone isolated from the root of the wild leguminous creeper Pueraria lobata (Willd) Ohwi) could prevent isoprenaline-induced myocardial fibrosis in mice, and its mechanisms might be related to reduction of transforming growth factor-β1 expression via activation of peroxisome proliferator-activated receptor α/γ and subsequent inhibition of nuclear factor-κB in myocardial tissue.
In the study of "Phytoestrogens: implications in neurovascular research" by Lephart ED, Porter JP, Hedges DW, Lund TD, Setchell KD., posted in US National Library of Medicine National Institutes of Health found that health effects of estrogen, isoflavones and their hormonal mechanism of action, brain penetration by isoflavones, heath effects of isoflavones, and effects of isoflavones on vascular, neuroendocrine, and cognitive function. Because of their diverse health effects and widespread availability in soy foods, dietary phytoestrogens merit continued research into their effects on human health and cognitive function.
Wednesday, December 7, 2011
In the study of "Vasorelaxant and antioxidant activity of the isoflavone metabolite equol in carotid and cerebral arteries" by Jackman KA, Woodman OL, Chrissobolis S, Sobey CG.. posted in US National Library of Medicine National Institutes of Health, found that Equol possesses substantial vasodilator and weak antioxidant activity in cerebral arteries, with similar activity to daidzein, whereas in hypertension the vasorelaxant response to equol, but not daidzein, is preserved. However, daidzein possesses comparable direct vascular effects with equol, without the need for intestinal conversion to equol. Nevertheless, equol may represent a more useful therapeutic agent during cerebral vascular disease.
In the study of "Memory performance of hypercholesterolemic mice in response to treatment with soy isoflavones" by Liu YQ, Xin TR, Lü XY, Ji Q, Jin Y, Yang HD., posted in US National Library of Medicine National Institutes of Health, found that SI improve the memory performance of hypercholesterolemic mice, and the mechanism underlying the improvement might closely correlate with its roles in decreasing high blood lipid levels and modulating the metabolism of neurotransmitters such as acetylcholine and amino acids in brain areas of hypercholesterolemic mice.
In the investigation of "Pre-treatment effect of different doses of soy isoflavones on spatial learning and memory in an ovariectomized animal model of Alzheimer's disease" by Sarkaki A, Amani R, Badavi M, Moghaddam AZ, Aligholi H, Safahani M, Haghighizadeh MH., posted in US National Library of Medicine National Institutes of Health, found that Soy meal diet (with or without isoflavone) in ovariectomized rats with Alzheimer's disease caused improvement of performance across 18 trials of Acquisition. Our results suggest that soy meal is a potential alternative to estrogen in the prevention and treatment of Alzheimer's disease.
In the study of "Preventive effects of soy meal (+/- isoflavone) on spatial cognitive deficiency and body weight in an ovariectomized animal model of Parkinson's disease" by Sarkaki A, Badavi M, Aligholi H, Moghaddam AZ., posted in US National Library of Medicine National Institutes of Health, found that long-duration dietary soy meal may have the potential neuroprotective effect against post-menopausal cognitive deficiency induced by degeneration of nigrostriatal dopaminergic system and constant body weight during post-menopausal life cycle.
Sunday, December 4, 2011
In the study of "Genistein reduces glycosaminoglycan levels in a mouse model of mucopolysaccharidosis type II" by Friso A, Tomanin R, Salvalaio M, Scarpa M, posted in US National Library of Medicine National Institutes of Health, found that Urinary GAG levels were reduced after 10 weeks' treatment with genistein at either 5 or 25 mg.kg(-1).day(-1). In tissue samples from liver, spleen, kidney and heart, a reduction in GAG content was observed with both dosages, after 10 weeks' treatment. Decreased GAG deposits in brain were observed after genistein treatment in some animals.
In the study of "Soy protein diet increases skilled forelimb reaching function after stroke in rats" by Cheatwood JL, Burnet D, Butteiger DN, Banz WJ., posted in US National Library of Medicine National Institutes of Health, found that rats receiving the soy protein-containing diet (SP) demonstrated less severe reaching deficits than rats fed the Na caseinate-containing diet (CAS) (p<0.05).
In the study of "A galactose-free diet enriched in soy isoflavones and antioxidants results in delayed onset of symptoms of Krabbe disease in twitcher mice" by Pannuzzo G, Cardile V, Costantino-Ceccarini E, Alvares E, Mazzone D, Perciavalle V., posted in US National Library of Medicine National Institutes of Health, found that a time-dependent and concentration-dependent decrease of OLP-II viability on exposure to psychosine and dose-dependent protection with the antioxidants xanthophylls and glutathione.
In the study of "The correlation between dietary soy phytoestrogens and neuropathic pain behavior in rats after partial denervation" by Shir Y, Campbell JN, Raja SN, Seltzer Z. posted in US National Library of Medicine National Institutes of Health, indicated that this report is the first to show that, at certain plasma concentrations, phytoestrogens reduce neuropathic pain in rats. IMPLICATIONS: Dietary soy suppresses neuropathic pain in rats after partial sciatic nerve ligation. Some of the pain-suppression properties of soy can be attributed to phytoestrogens, isoflavones abundantly found in soy products
In the study of "Randomized, controlled trial of phytoestrogen in the prophylactic treatment of menstrual migraine" by Burke BE, Olson RD, Cusack BJ. posted in US National Library of Medicine National Institutes of Health, found that forty-nine patients were randomized to receive either placebo, or a daily combination of 60 mg soy isoflavones, 100 mg dong quai, and 50 mg black cohosh, with each component standardized to its primary alkaloid. Patients received study medication for 24 weeks. Average frequency of menstrually associated migraine attacks during weeks 9-24 was reduced from 10.3 +/- 2.4 (mean +/- s.e.m.) in placebo treated patients to 4.7 +/- 1.8 (P < 0.01) in patients treated with the phytoestrogen preparation.
In the study of "Molecular design of seed storage proteins for enhanced food physicochemical properties" by Tandang-Silvas MR, Tecson-Mendoza EM, Mikami B, Utsumi S, Maruyama N., posted in US National Library of Medicine National Institutes of Health, found that Recombinant technology and protein engineering are two of the tools in biotechnology that have been used in producing soybean proteins with better gelling property, solubility, and emulsifying ability. This article reviews the molecular basis for the logical and precise protein designs that are important in obtaining the desired improved physicochemical properties.
Friday, December 2, 2011
In the study of "Soy protein isolate and its hydrolysate reduce body fat of dietary obese rats and genetically obese mice (yellow KK)" by Aoyama T, Fukui K, Takamatsu K, Hashimoto Y, Yamamoto T., posted in US National Library of Medicine National Institutes of Health, found that Body-fat content in mice fed SPI and SPI-H diets was significantly lower than in those fed the casein diet. In rats, plasma total cholesterol level was lower with the SPI-H diet, and plasma glucose level was lower with the SPI and SPI-H diets than with the casein diet. These results indicate that SPI and SPI-H are suitable protein sources in energy-restricted diets for the treatment of obesity.
In the study of "Soy milk and dairy consumption is independently associated with ultrasound attenuation of the heel bone among postmenopausal women: the Adventist Health Study-2" by Matthews VL, Knutsen SF, Beeson WL, Fraser GE., posted in US National Library of Medicine National Institutes of Health, found that Among individual dairy products, only cheese showed an independent and significant protection (OR = 0.28; 95% CI, 0.12-0.66; P(trend) = .004) for women eating cheese more than once per week vs those who ate cheese less than once a week. We concluded that osteoporosis is inversely associated with soy milk intake to a similar degree as dairy intake after accounting for age, body mass index, and estrogen use.
In the study of "The role of milk- and soy-based protein in support of muscle protein synthesis and muscle protein accretion in young and elderly persons" by Phillips SM, Tang JE, Moore DR., posted in US National Library of Medicine National Institutes of Health found that that whey protein is better able to support MPS than is soy protein, a finding that may explain the greater ability of whey protein to support greater net muscle mass gains with resistance exercise. This review focuses on evidence showing the differences in responses of MPS, and ultimately muscle protein accretion, to consumption of milk- and soy-based supplemental protein sources in humans.
By Everblest, Added March 08, 2004 | Recipe #86124, posted in Food.com (Sources)
Total Time: 1 hrs 50 mins
Prep Time: 1 hrs 5 mins
Cook Time: 45 mins
- 2 cups soybeans
- 1 medium onion
- 5 slices cooked and crumbled bacon
- 8 ounces feta cheese
- 1 1/2 cups cottage cheese
- 1 egg
- 1 bag frozen spinach
- Soak soybeans overnight in at least six cups of water.
- Cook soybeans in new water until tender.
- 3Thaw spinach in a bowl in the microwave.
- 4Saute onion (You could add one green pepper if you like.) Mix soybeans, crumbled bacon bits, onions and spinach together and spread in a large casserole dish.
- In a separate bowl, mix crumbled feta cheese, cottage cheese, and one egg.
- Spread cheese mixture over soybeans.
- Bake in 350 degree F oven 45 minutes until topping is brown and casserole is heated through.
- Variations: Use fresh spinach or broccoli or frozen broccoli.
- Note: You may need two eggs for binding the cheese to soybeans if feta is particularly dry.
- Sometimes I dust the top with a bit of paprika for color not for taste.
- You can use more or less bacon.
- It is just a teaser to get them to try it.
- I've made it without the bacon for a vegetarian friend of mine and she loved it.
Posted in wheat-free-meat-free.blogspot.com/ (Sources)
1 cup dried soybeans (makes 2 cups cooked beans)
1 Tbsp. olive oil
1 large onion, peeled and chopped (everything gets a medium chop)
1 large carrot, peeled and chopped
2 ribs celery, chopped
3 cloves garlic, peeled and chopped
1/2 green pepper, seeded and chopped
1 (14.5 oz.) can diced tomatoes
8-10 mushrooms, sliced
1 tsp. dried thyme
1 tsp. dried rosemary, crumbled
Salt and pepper to taste
1 Tbsp. butter
1 Tbsp. olive oil
1/4 cup brown rice flour
1 cup fresh bread crumbs (I used 2 slices Rudi's Gluten Free Wheat Bread)
1/3 cup grated Parmesan cheese
2 Tbsp. chopped fresh parsley
Soak soybeans overnight in water to cover. Drain and place in a medium saucepan with fresh water to cover. Bring to a boil. Turn heat to simmer and cook, covered, until beans are tender, 45 minutes to an hour. Drain beans, but reserve bean liquid.
Heat 1 Tbsp. olive oil in frying pan. Add onions and cook until softened, about 5 minutes. Add in carrots, celery, garlic, and green pepper. Cook another 2-3 minutes, stirring. Add 1 cup reserved bean broth and simmer over low heat, until carrots are crisp-tender, about 5-7 minutes more.
Add tomatoes (and their juice)and simmer another 5 minutes. Then, using a slotted spoon, remove all the simmered vegetables to the bowl with the cooked soybeans and mix well. Pour pan juices into a large measuring cup and add in enough bean broth to measure 2 cups. Reserve.
Wipe frying pan with a cloth or paper towel to dry. Add sliced mushrooms to pan and saute over medium heat until browned, about 3-4 minutes, stirring frequently. Mix mushrooms in with beans and sauteed vegetables. Add thyme, rosemary and salt and pepper to taste.
Turn mixture into a 1-1/2 quart casserole dish.
Heat oven to 375 degrees F.
Heat butter and 1 Tbsp. olive oil in frying pan. Whisk in rice flour to make a roux. Slowly add in reserved pan juice/bean stock mixture, whisking constantly to keep lumps from forming. Add salt and pepper to taste. Simmer, stirring, until sauce thickens, about 4-5 minutes. Pour sauce over vegetables in casserole dish.
Blend bread crumbs and Parmesan. Sprinkle over bean casserole. Drizzle a little extra olive oil over the top and then pop in the oven and bake for 45 minutes, or until bubbly and crumb topping is lightly browned and CRISPY.
Garnish with chopped parsley.
Total Time: 45 mins
Prep Time: 5 mins
Cook Time: 40 mins
- 125 g soybeans, soaked overnight
- 2 cups water
- 2 teaspoons vegetable oil
- 3/4 medium onion, chopped
- 2 tablespoons tomato paste
- 1/2 teaspoon mustard seeds
- 1/4 teaspoon red chili powder
- 1/4 teaspoon garam masala powder (optional)
- 2 tablespoons cilantro leaves, chopped
- Bring a pot of water (2 cups) to a boil, lower flame, add salt to taste (around 1/4 tsp), and cook the pre-soaked soy beans for about 30 minutes, or until cooked.
- While the beans are cooking, heat oil in a saucepan on a medium-high flame and add the mustard seeds.
- When they start sputtering, add the chopped onions and sauté until they turn brown.
- Now add the tomato paste, red chili powder, garam masala powder, and sauté for about 5 minutes.
- Add the cooked soy beans to the saucepan, mix well and sauté for another 5 minutes.
- Remove from flame, garnish with chopped cilantro and serve hot!
Saturday, November 19, 2011
In the study of "Vascular Effects of Phytoestrogens and Alternative Menopausal Hormone Therapy in Cardiovascular Disease" by Gencel VB, Benjamin MM, Bahou SN, Khalil RA., posted in US National Library of Medicine National Institutes of Health, researchers found that the WHO-CARDIAC study supported that consumption of high soybean diet is associated with lower mortalities from coronary artery disease. However, as with estrogen, there has been some discrepancy between the experimental studies demonstrating the vascular benefits of phytoestrogens and the data from clinical trials. This is likely because the phytoestrogens clinical trials have been limited in many aspects including the number of participants enrolled, the clinical end points investigated, and the lack of long-term follow-up. Further investigation of the cellular mechanisms underlying the vascular effects of phytoestrogens and careful evaluation of the epidemiological evidence and clinical trials of their potential vascular benefits would put forward the use of phytoestrogens as an alternative MHT for the relief of menopausal symptoms and amelioration of postmenopausal CVD.
According to the study of "Soy isoflavones radiosensitize lung cancer while mitigating normal tissue injury" by Hillman GG, Singh-Gupta V, Runyan L, Yunker CK, Rakowski JT, Sarkar FH, Miller S, Gadgeel SM, Sethi S, Joiner MC, Konski AA.,posted in US National Library of Medicine National Institutes of Health, researchers found that Soy isoflavones augment destruction of A549 lung tumor nodules by radiation, and also mitigate vascular damage, inflammation and fibrosis caused by radiation injury to normal lung tissue. Soy could be used as a non-toxic complementary approach to improve RT in NSCLC.
In the study of "Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen" by Ide H, Tokiwa S, Sakamaki K, Nishio K, Isotani S, Muto S, Hama T, Masuda H, Horie S., posted in US National Library of Medicine National Institutes of Health, researchers found that the production of prostate-specific antigen(PSA) were markedly decreased by the combined treatment of isoflavones and curcumin in prostate cancer cell line, LNCaP. The expression of the androgen receptor was also suppressed by the treatment. In clinical trials, PSA levels decreased in the patients group with PSA >or= 10 treated with supplement containing isoflavones and curcumin (P = 0.01) and concluded that isoflavones and curcumin could modulate serum PSA levels. Curcumin presumably synergizes with isoflavones to suppress PSA production in prostate cells through the anti-androgen effects.
In the study of "[Effects of soy isoflavones and major active component genistein on the expression of ovarian estrogen receptor-α in rats].[Article in Chinese]" by Zhang YH, Pang HY, Xiao XH, Wen HX, Ni J., posted in US National Library of Medicine National Institutes of Health, researchers found that Soy isoflavones can up-regulate the expressions of ER-α mRNA and protein in senile rat ovaries. As a major active component of soy isoflavones, genistein can regulate the expressions ER-α mRNA in granulosa cells of rat ovaries. Such an effect is concentration-dependent. And 1-10 µmol/L genistein may up-regulate the expression of ER-α mRNA.
Tuesday, November 15, 2011
According to the study of "Soy lecithin supplementation alters macrophage phagocytosis and lymphocyte response to concanavalin A: a study in alloxan-induced diabetic rats" by Miranda DT, Batista VG, Grando FC, Paula FM, Felício CA, Rubbo GF, Fernandes LC, Curi R, Nishiyama A., posted in US National Library of Medicine National Institutes of Health, researchers found that Soy lecithin supplementation significantly increased both macrophage phagocytic capacity (+29%) in non-diabetic rats and the lymphocyte number in diabetic rats (+92%). It is unlikely that plasma lipid levels indirectly affect immune cells, since plasma cholesterol, TAG, or phospholipid content was not modified by lecithin supplementation. In conclusion, lymphocyte and macrophage function were altered by lecithin supplementation, indicating an immunomodulatory effect of phosphatidylcholine.
In the study of 'Antiatherogenic and antiperoxidative effects of garlic and soy proteins in alcohol fed rats" by Rajasree CR, Rajmohan T, Augusti KT., posted in US National Library of Medicine National Institutes of Health, researchers found that GP(garlic proteins) feeding showed a better effect than SP(soy proteins) in lowering serum and heart total cholesterol, and in maintaining GPx( glutathione peroxidase) at near normal level, while SP feeding showed a better effect in lowering serum FFA(free fatty acid) level and maintaining GR(glutathione reductase) activity at near normal level. In suppressing incorporation of labeled acetate into serum cholesterol, GP feeding showed a better effect than SP. Antiatherogenic and antiperoxidative effects of these proteins may be due to lower lysine/arginine ratio.
According to the study of "Soy lecithin replaces egg yolk for cryopreservation of human sperm without adversely affecting postthaw motility, morphology, sperm DNA integrity, or sperm binding to hyaluronate' by Reed ML, Ezeh PC, Hamic A, Thompson DJ, Caperton CL., posted in US National Library of Medicine National Institutes of Health, researchers found that Soy lecithi enhances  recovery of motile sperm,  maintenance of sperm cell morphology,  maintenance of the ability of sperm to bind to hyaluronate in vitro, or  maintenance of sperm DNA integrity.
In the study of "Influence of soy lecithin administration on hypercholesterolemia" by Mourad AM, de Carvalho Pincinato E, Mazzola PG, Sabha M, Moriel P. posted in US National Library of Medicine National Institutes of Health, researchers found that a significant reduction in total cholesterol and LDL-cholesterol concentrations was observed during the first month of treatment, suggesting that the administration of soy lecithin daily may be used as a supplemental treatment in hypercholesterolemia.
In the study of "Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress" by Hellhammer J, Fries E, Buss C, Engert V, Tuch A, Rutenberg D, Hellhammer D., posted in US National Library of Medicine National Institutes of Health, researchers found that PAS seemed to exert a specific positive effect on emotional responses to the (Trier Social Stress Test)TSST. While the placebo group showed the expected increase in distress after the test, the group treated with 400 mg PAS showed decreased distress.
Wednesday, November 9, 2011
In the study of "Soy protein versus soy phytoestrogens in the prevention of diet-induced coronary artery atherosclerosis of male cynomolgus monkeys" by Anthony MS, Clarkson TB, Bullock BC, Wagner JD., posted in US National Library of Medicine National Institutes of Health,resreachers found that The beneficial effects of soy protein on atherosclerosis appear to be mediated primarily by the phytoestrogen component. Testicular weights were unaffected by the phytoestrogens.
In the study of "Effects of soy vs. casein protein on body weight and glycemic control in female monkeys and their offspring" by Wagner JD, Jorgensen MJ, Cline JM, Lees CJ, Franke AA, Zhang L, Ayers MR, Schultz C, Kaplan JR., posted in US National Library of Medicine National Institutes of Health, researchers indicated that Glucose tolerance tests in adult females were not significantly different with diet, but offspring eating TAD soy had increased glucose disappearance with overall lower glucose and insulin responses to the glucose challenge compared with typical American diet (TAD) casein.
According to tghe sstudy of "Epigenetic changes with dietary soy in cynomolgus monkeys" by Howard TD, Ho SM, Zhang L, Chen J, Cui W, Slager R, Gray S, Hawkins GA, Medvedovic M, Wagner JD., posted in US National Library of Medicine National Institutes of Health, researchers found that eating two high-fat, typical American diets (TAD) with similar macronutrient contents, with or without soy protein. DNA methylation status was successfully determined for 80.6% of the probes in at least one tissue using Illumina's HumanMethylation27 BeadChip and concluded that the use of the HumanMethylation27 BeadChip in cynomolgus monkeys and identify epigenetic changes associated with dietary interventions with soy protein that may potentially affect the etiology of complex diseases.
Friday, November 4, 2011
According to the study of `Dietary soy isoflavone induced increases in antioxidant and eNOS gene expression lead to improved endothelial function and reduced blood pressure in vivo`by Mahn K, Borrás C, Knock GA, Taylor P, Khan IY, Sugden D, Poston L, Ward JP, Sharpe RM, Viña J, Aaronson PI, Mann GE. posted in US National Library of Medicine National Institutes of Health,
In the stdy of `Two-year follow-up of Sanfilippo Disease patients treated with a genistein-rich isoflavone extract: assessment of effects on cognitive functions and general status of patients` by Piotrowska E, Jakobkiewicz-Banecka J, Maryniak A, Tylki-Szymanska A, Puk E, Liberek A, Wegrzyn A, Czartoryska B, Slominska-Wojewodzka M, Wegrzyn G., posted in US National Library of Medicine National Institutes of Health, researchers found that the treatment of Sanfilippo patients with a genistein-rich soy isoflavone extract (called gene expression-targeted isoflavone therapy [GET IT]) may be effective in either inhibition (in some patients) or slowing down (in other patients) of behavioral and cognitive problems over a longer period. An increased dose of genistein may improve the efficacy of the treatment.
According to the study of `Monitoring sunitinib-induced vascular effects to optimize radiotherapy combined with soy isoflavones in murine xenograft tumor`by Hillman GG, Singh-Gupta V, Al-Bashir AK, Yunker CK, Joiner MC, Sarkar FH, Abrams J, Haacke EM., posted in US National Library of Medicine National Institutes of Health, researchers found that that soy could protect the vasculature of normal tissue from the adverse effects of sunitinib. An antiangiogenic approach that only partially destroys inefficient vessels could potentially increase the efficacy and delivery of cytotoxic therapies and radiotherapy for unresectable primary renal cell carcinoma tumors and metastatic disease.
Wednesday, November 2, 2011
By: Sue Lau, posted in All recipes.com (Source)
- 1 tablespoon toasted sesame oil
- 1 tablespoon soy sauce
- 3 cloves garlic, minced
- 1 teaspoon brown sugar
- 1 1/2 pounds fresh asparagus, trimmed
- 2 tablespoons toasted sesame seeds
- Preheat grill for high heat.
- In a bowl, mix sesame oil, soy sauce, garlic, and brown sugar. Place asparagus in the bowl, and toss to coat.
- Lightly oil a fine-mesh grill grate. Place asparagus on grate, and cook 8 minutes, until tender but firm. Garnish with sesame seeds to serve.
Recipe By: STEVEANDANGELA . posted in All recipes (Source)
Prep Time: 5 Min
Cook Time: 10 Min
Ready In: 15 MinServing: 2
- 2 tablespoons butter
- 1 (8 ounce) package sliced white mushrooms
- 2 cloves garlic, minced
- 2 teaspoons soy sauce
- ground black pepper to taste
- Melt the butter in skillet over medium heat; add the mushrooms; cook and stir until the mushrooms have softened and released their liquid, about 5 minutes. Stir in the garlic; continue to cook and stir for 1 minute. Pour in the soy sauce; cook the mushrooms in the soy sauce until the liquid has evaporated, about 4 minutes.
According to the study of "Nutritional aspects of second generation soy foods" by Alezandro MR, Granato D, Lajolo FM, Genovese MI." , posted in US National Library of Medicine National Institutes of Health, researchers found that the soy-based foods do not present a significant content of isoflavones when compared with the grain, and their in vitro antioxidant capacity is not related with these compounds but rather to the presence of other phenolics and synthetic antioxidants, such as sodium erythorbate. However, they may represent alternative sources and provide soy protein, isoflavones, and vegetable fat for those who are not ready to eat traditional soy foods.
According to the study of "Anti-inflammatory effects of glyceollins derived from soybean by elicitation with Aspergillus sojae" by Kim HJ, Sung MK, Kim JS., posted in US National Library of Medicine National Institutes of Health, researchers indicated that Glyceollins exert an anti-inflammatory effect, which is mediated through the inhibition of NF-κB activation in LPS-activated murine RAW264.7 cells. Glyceollins merit further study as potential therapeutic agents for inflammatory disorders.
Friday, October 28, 2011
In the study of "Dietary soy-derived isoflavone phytoestrogens. Could they have a role in coronary heart disease prevention?" by Tikkanen MJ, Adlercreutz H., posted in US National Library of Medicine National Institutes of Health, researchers found that , lipophilic phytoestrogen derivatives could be incorporated into LDLs, increasing their oxidation resistance and antiproliferative efficacy ex vivo, both of which are, in theory, antiatherogenic effects
In the study of "Soy-derived isoflavones inhibit HeLa cell growth by inducing apoptosis" by Xiao JX, Huang GQ, Geng X, Qiu HW., posted in US National Library of Medicine National Institutes of Health, showed that SI-I inhibited HeLa cell growth through inducing apoptosis via the mitochondrial pathway and comparisons with reported data indicated that synergistic effect existed between the isoflavone species contained in SI-I. It is proposed that natural soy-derived isoflavones are potential candidates as chemotherapeutic agents against human cervical cancer.
In the study of "miRNAs Differentially Expressed in Prostate Cancer Cell Lines after Soy Treatment" by Rabiau N, Trraf HK, Adjakly M, Bosviel R, Guy L, Fontana L, Bignon YJ, Bernard-Gallon DJ., posted in US National Library of Medicine National Institutes of Health, researchers found that out of 377 miRNAs tested, 180, 170 and 150 miRNAs were amplified with 2% of variation in the triplicate in PC-3, DU145 and LNCap cells, respectively, and only 5 miRNAs for PC-3 and DU145 cells and 4 miRNAs for LNCap exhibited a significant change in their expression. Treatment with genistein or daidzein had similar effects on miRNA regulation to those of 5-AZA treatment and concluded that this work demonstrated a new role of isoflavones on the regulation of miRNAs in prostate cancer.
Tuesday, October 25, 2011
According to the study of "Effect of high-dose isoflavones on cognition, quality of life, androgens, and lipoprotein in post-menopausal women" by Basaria US, Wisniewski A, Dupree K, Bruno T, Song MY, Yao F, Ojumu A, John M, Dobs AS., posted in S National Library of Medicine National Institutes of Health, researchers found that High-dose isoflavones is associated with improved QOL among women who have become menopausal recently. Hence, the timing of isoflavone supplementation with regards to the onset of menopause appears to be important. The use of isoflavones, as an alternative to estrogen therapy, may be potentially useful and seemingly safe in this group of women who are looking for relief from menopausal symptoms.
According to the study of "Serum IGF-1 concentrations change with soy and seaweed supplements in healthy postmenopausal American women" by Teas J, Irhimeh MR, Druker S, Hurley TG, Hébert JR, Savarese TM, Kurzer MS., posted in posted in US National Library of Medicine National Institutes of Health, researchers indicated that Insulin-like growth factor 1 (IGF-1) is an anabolic hormone important for growth and development. However, high-circulating serum concentrations in adults are associated with increased risk of postmenopausal breast cancer....and concluded that Concurrent seaweed and soy consumption may be important in modifying the effect of soy on IGF-1 serum concentrations.
In the study of "Combined effects of MDM2 SNP309 and TP53 R72P polymorphisms, and soy isoflavones on breast cancer risk among Chinese women in Singapore" by Koh WP, Van Den Berg D, Jin A, Wang R, Yuan JM, Yu MC., posted in US National Library of Medicine National Institutes of Health, researchers found that support experimental data implicating combined effects of MDM2 protein and the p53-mediated pathway in breast carcinogenesis, and suggest that soy isoflavones may exert protective effect via down-regulation of the MDM2 protein.
- 50 g cashew nuts, toasted
- 300 g glass vermicelli or 'dongfen'
- 1 stalk fresh coriander, chopped coarsely
- 8 mint leaves, chopped coarsely
- 5 basil leaves, chopped coarsely
- 2 tbsp fish sauce,
- 2 tbsp soy sauce
- Cut the following into long strands
- 200 g fresh tofu,
- 1 carrot,
- 1 cucumber,
- 20 g young ginger
- 1 stalk spring onion
- 1 fresh red chili
- 4 tbsp lime juice
Soak the transparent vermicelli with lukewarm water for about 5 minutes, or till breakable when pulled.
Combine all ingredients, except tofu, and stir carefully.
Add in tofu last and mix carefully, not to break it too much.
Chill for 1 hour.