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Sunday, April 22, 2012

Soy and leukemia

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "The soyabean isoflavones genistein (GEN) and daidzein (DA) are popular presented in diet. Isoflavones have a variety of biological activities including antioxidant and anticancer properties" by Zhang SJ, Sun D, Hao JB, Wei YF, Yin LF, Liu X. posted in US National Library of Medicine National Institutes of Health, researchers found that GEN inhibited cell proliferation and enhance cell apoptosis, lipid peroxidation, and DNA damage in ALA-PDT on K562 cells. However, DA did not enhance cell apoptosis, lipid peroxidation, and DNA damage in ALA-PDT. In conclusion, the results suggested that soy consumption during PDT did not decrease the effectiveness of cancer therapy on malignant cells.

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