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Tuesday, April 17, 2012

soy isoflavone metabolism and accumulation in prostatic fluid

 Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

 In the study of "Long-term dietary habits affect soy isoflavone metabolism and accumulation in prostatic fluid in caucasian men. by Hedlund TE, Maroni PD, Ferucci PG, Dayton R, Barnes S, Jones K, Moore R, Ogden LG, Wähälä K, Sackett HM, Gray KJ., posted in US National Library of Medicine National Institutes of Health, researchers found that Equol production was not linked to age, BMI, or the consumption of yogurt, dairy, fruit, or American-style fast food. Daidzein and its metabolites (but not genistein) were typically present at higher levels in prostate fluid than plasma (median = 4-13 times that in plasma). In conclusion, our data suggest that the ability of Caucasian men to produce equol is favorably influenced by the long-term consumption of high amounts of soy and the consumption of meat. Last, the high concentrations of isoflavonoids in prostatic fluid increases the potential for these compounds to have direct effects in the prostate.

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