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Monday, June 25, 2012

Pharmaceutical and nutraceutical management of canine osteoarthritis

 Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health


In the study of Pharmaceutical and nutraceutical management of canine osteoarthritis: present and future perspectives" by Henrotin Y, Sanchez C, Balligand M., posted in US National Library of Medicine National Institutes of Health, indicated that until now, the therapeutic management of OA in dogs has been dominated by nonsteroidal anti-inflammatory drugs, but some new compounds, including diacerhein, with potential structure-modifying effects, are already used to treat OA in humans and could be helpful to manage OA in the dog. In addition, novel nutraceuticals, such as avocado/soybean unsaponifiable substances, have shown symptomatic effects in knee OA in humans, and could offer an alternative to prevent OA progression. This paper provides an overview of recent discoveries in the pathophysiology and in the therapeutic management of osteoarthritis in dogs.

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