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Thursday, March 14, 2013

Anticancer and antimetastatic properties of doenjang

Posted by Chantel M. research contributed by US National Library of Medicine National Institutes of Health 
Fermented soy foods, such as doenjang, are important components of the Korean diet.  
In the study to assess the effects of methanol extracts from doenjang prepared with long-term fermentation on tumor formation, natural killer cell activity in spleen, and glutathione S-transferase activity in liver in sarcoma-180 cell-transplanted mice, posted in PubMed, showed that doenjang fermented for 24 mo exhibited a two- to three-fold increase in antitumor effects on sarcoma-180-injected mice and antimetastatic effects in colon 26-M 3.1 cells in mice compared with the 3- or 6-mo fermented doenjang. The 24-mo fermentation was the most effective in preventing cancer by decreasing tumor formation and increasing natural killer cell activity in spleens and glutathione S-transferase activity in livers of mice.

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