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Monday, June 10, 2013

Isoflavones and cognitive function in older women

 Posted by Chantel Martiromo. research contributed by PubMed

In the study to examine the effects of a dietary supplement of isoflavones on cognitive function in postmenopausal women, by the University of California, posted in PubMed,showed that at baseline, all women were cognitively intact; there were no significant differences by treatment assignment in age, education, depressed mood, or cognitive function (all P values > 0.10). Compliance was 98% and 97%, respectively, in the placebo and treatment groups; all women took at least 85% of their pills. The women in the treatment group did consistently better, both as compared with their own baseline scores and as compared with the placebo group responses at 6 months. Comparisons of percentage change in cognitive function between baseline and follow-up showed greater improvement in category fluency for women on active treatment as compared with the case of those on placebo (P = 0.02) and showed (nonsignificantly) greater improvement on the two other tests of verbal memory and Trails B.

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