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Wednesday, July 31, 2013

Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis

Posted by Chantel Martiromo. research contributed by PubMed

In the study to investigate whether genes involved in AKT/nuclear factor kappa B signaling and/or gene-environment interactions between the genes and phytoestrogens may be susceptible factors for gastric cancer posted in PubMed, indicated that CDK1 and FAS genes involved in AKT signaling and influenced by anti-carcinogenic property of phytoestrogens can play a role as susceptible genetic factors in gastric carcinogenesis. FAS and MAP3K1 genes significantly interact with enterolactone, thereby modifying the individual's risk for gastric cancer.

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