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Thursday, August 14, 2014

Green Tea and Asthma

Posted by Chantel Martiromo

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and  muscles breathing , etc.
 Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. According to American academy, allergy, asthma and immunology, about 1 in 10 children (10%) had asthma and 1 in 12 adults (8%) had asthma in 2009. (about 25 million, or 8% of the U.S. population).

Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
According to the study at State University of New York Downstate Medical Center, green tea extract (GTE), and its major catechin, consisted an immunoregulatory effects through suppression of IgE production by peripheral blood mononuclear cells of allergic asthmatic patinets(30) and B cell production of IgE without inducing apoptosis(31). Other study suggested a anti asthmatic effect of aqueous extract of Camellia sinensis through increasing the expression level of tumor necrosis factor-beta and interferon-gamma and decreasing the expression of anti-asthmatic cytokines in the lung(32).


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References

(30) Green tea (Camelia sinensis) mediated suppression of IgE production by peripheral blood mononuclear cells of allergic asthmatic humans by Wu SY1, Silverberg JI, Joks R, Durkin HG, Smith-Norowitz TA.(PubMed)
(31) Green tea (Camelia sinensis) suppresses B cell production of IgE without inducing apoptosis by Hassanain E1, Silverberg JI, Norowitz KB, Chice S, Bluth MH, Brody N, Joks R, Durkin HG, Smith-Norowitz TA.(PubMed)
(32) An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers by Heo JC1, Rho JR, Kim TH, Kim SY, Lee SH.(PubMed)

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