Overcome Female Infertility - The Radioimmunoassays (RIAs)

Posted by Chantel Martiromo

Fertility is a natural process to insure the survival of human species. Through natural selection, we produce many offspring when the reproductive system works at it's peak in the suitable environment with plenty of food around. On the other hand, the reproductive system may completely shut down or work at it's minimum state and we produce less offspring, when the environment is hostile including less foods around, war, epidemic, but regardless of all these factors, most women are capable of conceiving during their menstrual cycle before menopause.

Radioimmunoassay (RIAs) is a very sensitive medical technique used to measure concentrations of antigens such as quantitating the binding, or the inhibition of binding, of a radio-labeled substance to an antibody which help your doctor to determine that the infertility is not or caused by hormone imbalance during menstrual cycle.

I. Procedure
By mixing a known quantity of an antigen and antibody with the sample of serum from a patient containing an unknown quantity, it helps to measure the interaction of testosterone, LH, FSH, prolactin hormones.

II. Diagnosis
After the uterine lining is shed and the previous menstrual cycle end. The surge of estrogen indicate the new menstrual cycle is begun. The levels of estrogen stimulate hypothalamus to secret gonadotropin releasing hormone (GnRH), it helps the pituitary gland to secret Follicle stimulated hormone (FSH) for production of eggs from the ovaries. When the eggs is mature, the production of luteinizing hormone (LH) causes mature egg being extruded from the ovaries a few days before ovulation and allows the cervix to produce the sperm friendly mucus, then the levels of progesterone surge to soften the lining of uterus for implantation of the embryo if fertilized, otherwise the uterine lining is shed and prepare the next menstrual cycle. Anything gone wrong in hormone secretion during this process will influence the quantitating the binding or the inhibition of binding, of a radio-labeled substance to an antibody and can be detected.

III. Risks
No risk is known.

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