Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health
In the study to investigate the effect of a soy
isoflavone extract over insulin sensitivity and plasma leptin levels.
Methods Eighty postmenopausal women were randomly assigned to
participate for 24 months either to a physical exercise and Mediterranean diet program (Control group: CG) or this intervention plus a daily oral intake of a soy isoflavone extract (Soy isoflavone group: SIG) by Llaneza P, González C, Fernández-Iñarrea J, Alonso A, Díaz F, Pérez-López FR.. posted in PubMed, found that At month 24, body mass index (BMI) was lower in the SIG as compared to
the CG. Fat mass, glucose, insulin, HOMA-IR, tumor necrosis factor-α
(TNF-α), Kupperman Index and Cervantes Scale values significantly
decreased in the SIG as compared to baseline and to CG values. Kupperman
scores and serum TNF-α levels significantly decreased in both studied
groups. No changes in plasma leptin levels were observed after 24 months
within and between groups.
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